Clinical, teaching, and research experience
Director of Gastroenterology, Aviation General Hospital · Director of Digestive Endoscopy Center
Jianguo Zhang
JIANGUO ZHANG · Chief Physician
Natural access ultra-minimally invasive digestive endoscopy
Minimally invasive endoscopic procedures completed
Patent applications and original device achievements
Papers, books, guidelines, and consensus contributions
Profile
About
Jianguo ZhangM.D., ProfessorChief Physician, Master's SupervisorHarvard Visiting Scholar
Prof. Jianguo Zhang is Director of Gastroenterology and Director of the Digestive Endoscopy Center at Aviation General Hospital. He focuses on early digestive cancer diagnosis and treatment, hepatobiliary-pancreatic endoscopic intervention, original NOEES techniques, and medical device translation.
His basic and clinical work focuses on hepatobiliary, pancreatic, gastric, and intestinal disease. He has completed more than 10,000 minimally invasive digestive endoscopy procedures and has extensive experience in complex digestive disease, advanced endoscopic surgery, and emerging endoscopic techniques.
He has pioneered procedures including ultra-minimally invasive gallbladder endoscopy, FV-ESD for early digestive tumors, and endoscopic internal-external drainage conversion (ETID), and was among the first to propose and systematically develop the NOEES concept.
Clinical Focus
Transoral gallbladder-preserving stone removal and ultra-minimally invasive endoscopic care for complex hepatobiliary-pancreatic diseases
Creator of the NOEES system
A natural access, zero-incision surgical philosophy using the body's native pathways to complete treatment.
Peroral gallbladder-preserving NOEES
The natural-orifice route reaches the bile duct and gallbladder without an abdominal incision to remove gallstones and polyps while preserving gallbladder function when appropriate.
Ultra-minimally invasive hepatobiliary and pancreatic endoscopy
Provides ERCP, EUS, EUS-BD, complex pancreatobiliary drainage, and endoscopic treatment of common bile duct and intrahepatic stones.
Endoscopic repair of esophagotracheal fistula
The Zhang closure method enables precise endoscopic treatment of fistulas under direct vision and supports ultra-minimally invasive repair of complex digestive tract defects.
Early diagnosis and treatment of digestive tumors
Focuses on screening, precise assessment, and curative endoscopic resection, including FV-ESD, to improve en bloc removal while supporting organ preservation and recovery.
Medical-engineering innovation and clinical translation
Connects original procedures, dedicated devices, and standardized clinical pathways from foundational research to practical clinical adoption.
Clinical Evidence
Gb-NOEES connects direct diagnosis, lesion removal, and gallbladder preservation
The transpapillary natural-orifice route reaches the gallbladder through the mouth, duodenum, bile duct, and cystic duct. It enables direct visualization, targeted pathology, and treatment without an abdominal incision.
International recognition
Selected for the DDW 2026 SSAT Presidential Plenary and Best of SSAT
The 20-patient gallbladder-polyp study was presented in the SSAT Presidential Plenary at DDW 2026 and included in the Best of SSAT segment. Earlier Gb-NOEES results were presented at UEG Week 2025.
Gallbladder-polyp organ-preservation cohort
A consecutive, single-center retrospective cohort of 20 patients with polyps measuring 0.6-3.5 cm, followed for 6-26 months.
100%technical success and pathological sampling
20/20target polyps completely removed
0major complications or conversions to open surgery
18/20cholesterol or inflammatory polyps
0recurrences during reported follow-up
20/20gallbladders preserved
100-patient Gb-NOEES clinical series
A single-center retrospective series covering gallstones, polyps, acute cholecystitis, and related gallbladder disease, with 2-26 months of follow-up.
99%overall technical success
4%overall complications
98%stone clearance (78/80)
100%complete polyp excision (15/15)
100%drainage success in acute cholecystitis (4/4)
2.5%stone recurrence (2/80)
A see, diagnose, treat, and preserve pathway
Natural access
Per-oral entry follows the native lumen to the gallbladder.
Direct visualization
Cholangioscopy examines the lesion inside the gallbladder.
Targeted treatment
Polyps, stones, or drainage needs are managed under direct view.
Pathology and preservation
Tissue diagnosis is obtained while the gallbladder is retained when appropriate.
Clinical Video
NOEES technique demonstration
Featured demonstration
Natural Orifice Endoscopic Surgery (NOEES)
Gallbladder polyp retrieval
Polyp retrieval · Case 01
Polyp retrieval · Case 02
Polyp retrieval · Case 03
Training & Career
Training, clinical leadership, publications, and device innovation
Training
Jan 2018 to Jun 2018, visiting scholar at the Endoscopy Center of Brigham and Women's Hospital, Harvard；Led RCT research on the Zhang Dissection Knife and Zhang Dissection Method；First and only Chinese digestive endoscopist invited to lead an original device RCT at Harvard
Brigham and Women's Hospital
Career
Since Jul 2014, Aviation General Hospital, Director roles in Gastroenterology and Digestive Endoscopy
Ultra-minimally invasive digestive endoscopy
Career
Jun 2008 to Jul 2014, Department of Gastroenterology, General Hospital of the Armed Police Forces
Ultra-minimally invasive digestive endoscopy
Research
Editor-in-chief of Endoscopic Retrograde Cholangiopancreatography and Endoscopic Ultrasound；Published 40+ papers, applied for nearly 60 patents, and translated multiple original techniques and devices
Publications, patents, and translation
Appointments & Honors
Selected Appointments
- Chair, China Digestive Endoscopy Collaborative Innovation Platform
- Deputy Head, MedTech Translation Group, Chinese Society of Digestive Endoscopy
- Council Member, China Association of Inventions
- Chair, NOEES Branch, Beijing Society of Integrative Medicine
- Director, Institute of Minimally Invasive Medical Translation, Huairou Science City
- Director, Minimally Invasive Medicine Center, National Animal Model Center
Selected Honors
- Gallbladder-polyp NOEES research selected for the DDW 2026 SSAT Presidential Plenary and Best of SSAT
- Original technique and device invited for RCT research at Brigham and Women's Hospital, Harvard
- Speaker at DDW, UEGW, APDW, and major Chinese digestive endoscopy meetings
- China Industry-University-Research Cooperation Innovation Award and medical innovation awards
- Outstanding Young Talent of AVIC and national youth federation member for central enterprises
Contact
Contact
Clinical Affiliation
- Hospital
- Aviation General Hospital
- Department
- Department of Gastroenterology / Aviation General Hospital Digestive Endoscopy Center
Contact Details
- [email protected]
- zhangjianguomd
This page is for academic profile and patient education. Clinical arrangements are subject to official hospital information.